"Zika-linked microcephaly was rare in early cases, but it’s only ‘tip of the iceberg’"


"In a commentary Rodrigues wrote for the Lancet, she used Nielsen-Saines’ data to suggest that the risk of microcephaly after a first trimester infection might be as high as 22 percent. Rodrigues teaches at the London School of Hygiene and Tropical Medicine.

She and Cauchemez agreed that the true picture is still coming into focus, and there will be more evidence on which to make such estimates soon. Nielsen-Saines and her group plan to issue an update on the women they are following — the cohort now has 300 pregnant women registered — in the next two months. Other groups in Brazil and Colombia will also be reporting results.

Likewise, Cauchemez noted that, as Nielsen-Saines reported, there is a spectrum of neurological health problems in babies born to women who were infected with Zika during pregnancy. And problems are evident even when the women were infected in the second and third trimesters.

“It’s not saying ‘If your child isn’t microcephalic, he’s fine.’ There could be other complications,” he noted."

"A recent study by American and Brazilian scientists reported that abnormalities were seen in 29 percent of fetuses carried by a group of women who were confirmed to have been infected with Zika during pregnancy."

“I personally thought that microcephaly was just the tip of the iceberg, that there was a whole host of conditions associated with this infection — which makes sense with all we know about congenital infections,” she said. “There’s never only one finding. There’s always a syndrome, you know? Many things.”  Click here for the full story.




Jill Malone